. Author manuscript; available in PMC: 2021 Jan 7.

Published in final edited form as: Ann Intern Med. 2019 Dec 10;172(1):12–21. doi: 10.7326/M19-0974

Table 2.

Standard Operating Characteristics from Application of the GRACE Model to the SILVER-AMI Validation Cohort for Death Within 180 Days (n = 1002)

Characteristic	Sensitivity (95% CI)^*
	0.70 (0.67–0.72)	0.74 (0.71–0.77)	0.81 (0.78–0.83)	0.85 (0.83–0.88)	0.92 (0.90–0.93)
Specificity (95% CI)	0.72 (0.70–0.75)	0.67 (0.64–0.70)	0.57 (0.54–0.60)	0.43 (0.40–0.46)	0.34 (0.31–0.37)
Positive predictive value (95% CI)	0.18 (0.16–0.21)	0.17 (0.14–0.20)	0.14 (0.12–0.17)	0.12 (0.10–0.14)	0.11 (0.10–0.13)
Negative predictive value (95% CI)	0.96 (0.95–0.98)	0.97 (0.96–0.98)	0.97 (0.96–0.98)	0.97 (0.96–0.98)	0.98 (0.97–0.99)

AMI = acute myocardial infarction; GRACE = Global Registry of Acute Coronary Events; SILVER-AMI = Comprehensive Evaluation of Risk in Older Adults with AMI.

Due to risk model differences, sensitivity values in Tables 2 and 3 are statistically equivalent rather than numerically identical.