Table 2.
Clinical history characteristics by TB treatment outcome in adolescents
| TB treatment outcome, n (%) | Total, n (%) (N = 725) | ||
|---|---|---|---|
| Unfavorable (n = 115) | Favorable (n = 610) | ||
| TB form | |||
| Pulmonary | 107 (93) | 583 (95.6) | 690 (95.2) |
| Pulmonary + extrapulmonary | 8 (7) | 27 (4.4) | 35 (4.8) |
| Type of TB | |||
| Retreatment | 20 (17.4) | 28 (4.6) | 48 (6.6) |
| New case | 95 (82.6) | 576 (94.4) | 671 (92.6) |
| Transferred | 0 | 6 (1) | 6 (0.8) |
| TB–HIV coinfection | |||
| HIV negative | 79 (68.6) | 513 (84.1) | 592 (81.6) |
| HIV positive | 18 (15.7) | 10 (1.6) | 28 (3.9) |
| HIV not performed/missing data | 18 (15.7) | 87 (14.3) | 105 (14.5) |
| Extreme vulnerability | |||
| Yes | 28 (24.3) | 54 (8.9) | 82 (11.3) |
| No | 87 (75.7) | 556 (91.1) | 643 (88.7) |
| Direct observed treatment | |||
| Yes | 55 (47.8) | 367 (60.2) | 422 (58.2) |
| No | 26 (22.6) | 132 (21.6) | 158 (21.8) |
| Missing data | 34 (29.6) | 111 (18.2) | 145 (20) |
| Homeless | |||
| Yes | 7 (6.1) | 4 (0.7) | 11 (1.5) |
| No | 83 (72.2) | 468 (76.7) | 551 (76) |
| Missing data | 25 (21.7) | 138 (22.6) | 163 (22.5) |
| Inmates | |||
| Yes | 2 (1.7) | 10 (1.6) | 12 (1.6) |
| No | 90 (78.3) | 463 (75.9) | 553 (76.2) |
| Missing data | 23 (20) | 137 (22.5) | 160 (2.2) |
| Illicit drug use | |||
| Yes | 23 (20) | 34 (5.6) | 57 (7.8) |
| No | 71 (61.7) | 466 (76.4) | 537 (74.1) |
| Missing data | 21 (18.3) | 110 (18) | 131 (18.1) |
| Alcohol abuse | |||
| Yes | 6 (5.2) | 6 (1) | 12 (1.7) |
| No | 99 (86.1) | 564 (92.5) | 663 (91.4) |
| Missing data | 10 (8.7) | 40 (6.5) | 50 (6.9) |
| Tobacco use | |||
| Yes | 10 (8.7) | 24 (3.9) | 34 (4.7) |
| No | 82 (71.3) | 480 (78.7) | 562 (77.5) |
| Missing data | 23 (20) | 106 (17.4) | 129 (17.8) |
| Comorbidities | |||
| Yes | 19 (3.1) | 1 (0.9) | 20 (2.8) |
| No | 591 (96.9) | 114 (99.1) | 705 (97.2) |
| Xpert testing | |||
| Yes | 54 (47) | 276 (45.2) | 330 (45.5) |
| No | 61 (53) | 334 (54.8) | 395 (54.5) |
| Xpert testing results | |||
| RIF sensitive | 44 (38.3) | 240 (39.3) | 284 (39.2) |
| RIF resistant | 3 (2.6) | 8 (1.3) | 11 (1.5) |
| Not detectable | 7 (6.1) | 28 (4.6) | 35 (4.8) |
| Not performed | 61 (53) | 334 (54.8) | 395 (54.5) |
| Baseline DST performed | |||
| Yes | 41 (35.7) | 187 (30.7) | 228 (31.4) |
| No | 74 (64.3) | 423 (69.3) | 497 (68.6) |
| Baseline DST results | |||
| First-line drug susceptible | 37 (32.2) | 169 (27.7) | 206 (28.4) |
| INH resistant | 1 (0.9) | 10 (1.6) | 11 (1.5) |
| RIF and INH resistant | 3 (2.6) | 4 (0.7) | 7 (1) |
| RIF resistant | 0 | 4 (0.7) | 4 (0.5) |
| Not performed | 74 (64.3) | 423 (69.3) | 497 (68.6) |
DST = drug susceptibility testing; INH = isoniazid; RIF = rifampicin; TB = tuberculosis.