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. 2020 Nov 7;12(11):1271. doi: 10.3390/v12111271

Figure 2.

Figure 2

Noncanonical cap-snatching. (A) In mRNA 3′ clusters, IAV mRNA transcription starts using the basepairing of between the -1 nt (G) of host capped small RNAs and an internal nt C embedded in a 5′CW (W represents A or U) sequence on template vRNAs. (B) In vRNA 5′ regions, IAV RdRP utilizes the -1 nt (G) of host capped small RNAs to anneal with the -2 C of template cRNAs, initiating capped vRNA synthesis.