Table 2.

Thermodynamic parameters calculated from ITC assays for the interaction between the Janus dendrimers and the compounds IA and TRIAC. K_a values are expressed in M⁻¹ and ΔG, ΔH and (−T·ΔS) are expressed in kcal/mol.

		Ka	ΔG	ΔH	−T·ΔS
(NH3+)8[GMPA]-[MPA](C17)2	IA	6.3 × 103	−5.2	−1.1	−4.1
	TRIAC	1.0 × 105	−6.8	−6.0	−0.8
(NH3+)8[GMPA]-[MPA](C17)4	IA	9.2 × 104	−6.8	−0.4	−6.4
	TRIAC	6.1 × 105	−7.9	−0.4	−7.5
(NH3+)8[MPA]-[GMPA](C17)2	IA	4.8 × 104	−6.4	−0.1	−6.3
	TRIAC	1.5 × 105	−7.1	−1.3	−5.8
(NH3+)8[MPA]-[GMPA](C17)4	IA	1.1 × 106	−8.2	0.7	−8.9
	TRIAC	8.8 × 104	−6.7	−15.8	9.1

Typical error in Ka is 30%, absolute error in ΔG is 0.2 kcal/mol, absolute errors in ΔH and −T·ΔS are 0.5 kcal/mol.