Table 3.
CC50 and EC40 values for the dendrimer/drug aggregates compared to free drug values.
[IA] (μM) | [TRIAC] (μM) | |||
---|---|---|---|---|
CC50 | EC40 | CC50 | EC40 | |
(NH3+)8[GMPA]-[MPA](C17)2 | >160 | 2.5–5 | >63 | 1 |
(NH3+)8[GMPA]-[MPA](C17)4 | >80 | 2.5 | >67 | 1 |
(NH3+)8[MPA]-[GMPA](C17)2 | >99 | >99 | >61 | 30–60 |
free drug | 300 | 175 | 188 | 20–40 |