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Niacin protected against CaCl2-induced AAA formation. CaCl2 was applied to the infrarenal aortae of C57Bl/6 mice. (A) AAA diameter (n = 13–14). (B) Representative histology; H&E, VVG (elastin fragmentation), Mac-3 (macrophages), and MMP-2/-9. Data were analysed using one-way ANOVA followed by Bonferroni post hoc analysis. CaCl2, calcium chloride; H&E, haematoxylin & eosin; L, lumen; Mac, macrophage; NA, nicotinic acid; VVG, Verhoeff-van Gieson.
