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. 2020 Nov 4;12(21):21253–21272. doi: 10.18632/aging.103848

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Copyright: © 2020 Chang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Effect of TGF-β1 on the collagen content of cultured SHED. (A) Collagen content of SHED after exposure to TGF-β1 for 5 days as measured by Sircol collagen assay. Results were expressed Mean ± SE. (B) Effect of SB431542 on the TGF-β1-induced increase in collagen content of SHED. (C) Effect of 5z-7oxozeaenol on the TGF-β1-induced increase in collagen content of SHED. (D) Effect of U0126 on the TGF-β1-induced increase in collagen content of SHED. (E) Effect of SB203580 on the TGF-β1-induced increase in collagen content of SHED. *Denotes statistically significant difference when compared to control, #denotes statistically significant difference when compared with TGF-β1 (5 ng/ml)-treated group.