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. 2020 Nov 7;12(21):21923–21941. doi: 10.18632/aging.104013

Table 1. GO analysis of genes with survival-associated AS events.

Ontology ID Description p. adjust Count
Biological process GO:0043547 positive regulation of GTPase activity 7.66E-04 51
GO:0051726 regulation of cell cycle 0.001398 17
GO:0006281 DNA repair 0.001411 26
GO:0043407 negative regulation of MAP kinase activity 0.003236 8
GO:0030522 intracellular receptor signaling pathway 0.004442 8
GO:0043484 regulation of RNA splicing 0.004573 7
GO:0009612 response to mechanical stimulus 0.004988 10
GO:0007265 Ras protein signal transduction 0.005109 11
GO:0007050 cell cycle arrest 0.005168 17
GO:0006351 DNA-templated transcription 0.005416 135
Molecular function GO:0005515 protein binding 3.77E-11 587
GO:0005085 guanyl-nucleotide exchange factor activity 9.02E-05 19
GO:0008017 microtubule binding 0.001328 24
GO:0003684 damaged DNA binding 0.002371 11
GO:0042802 identical protein binding 0.004441 60
GO:0008307 structural constituent of muscle 0.007928 8
GO:0005089 Rho guanyl-nucleotide exchange factor activity 0.010129 11
GO:0070300 phosphatidic acid binding 0.01015 5
GO:0004672 protein kinase activity 0.010378 32
GO:0033130 acetylcholine receptor binding 0.011224 4
Cellular component GO:0005829 cytosol 1.14E-11 261
GO:0005654 nucleoplasm 8.49E-11 224
GO:0005737 cytoplasm 8.81E-09 360
GO:0005634 nucleus 4.99E-05 346
GO:0005925 focal adhesion 6.65E-05 41
GO:0016607 nuclear speck 0.001156 23
GO:0045111 intermediate filament cytoskeleton 0.001594 10
GO:0005875 microtubule associated complex 0.001853 8
GO:0035267 NuA4 histone acetyltransferase complex 0.002072 6
GO:0005874 microtubule 0.002649 30