Table 3. Correlations between increased plasma levels of t-tau/Aβ species and patterns of cortical thinning.
Cortical region | CS (mm2) | r | p |
t-tau | |||
L inferior temporal | 410 | 0.52 | 10-4 |
L fusiform gyrus | 336 | 0.45 | 10-4 |
L temporal pole | 123 | 0.36 | 10-4 |
R lingual gyrus | 85 | 0.49 | 10-5 |
Aβ1-40 | |||
L middle temporal | 133 | 0.56 | 10-5 |
L parahippocampal | 59 | 0.47 | 10-4 |
Aβ1-42 | |||
L temporal pole | 115 | 0.5 | 10-4 |
L parahippocampal | 59 | 0.47 | 10-4 |
R lateral occipital | 176 | 0.6 | 10-5 |
CS: cluster size; it refers to the extent of significant correlations between plasma markers and cortical FDG uptake. Left (L) and right (R) cortical hemisphere. r: Pearson correlation coefficient; p: exact p-value (corrected for multiple comparisons).