Table 2. Top 10 genes with increased expression (based on fold change) in the younger group compared with the Older group.

Gene	Gene function	Fold change log2 [Older/Younger]	p value	Expression level in Younger (FPKM)	Expression level in Older (FPKM)
MAP3K15	Mitogen-activated protein kinase kinase kinase 15	-0.99	4.02×10−7	0.79	0.40
CHRM2	Cholinergic receptor muscarinic 2	-0.92	1.52×10−3	0.69	0.37
GALNT13	Polypeptide N-acetylgalactosaminyltransferase 13	-0.89	2.75×10−8	0.98	0.53
MATN3	Matrilin 3	-0.87	1.99×10−9	2.89	1.58
ELMOD1	ELMO domain containing 1	-0.87	2.69×10−4	0.47	0.26
SHISA2	Shisa family member 2	-0.83	5.52×10−6	0.92	0.52
FIBIN	Fin bud initiation factor homolog (zebrafish)	-0.81	2.42×10−8	1.81	1.04
B3GALT2	Beta-1,3-galactosyltransferase 2	-0.80	3.13×10−6	0.67	0.38
P2RY1	Purinergic receptor P2Y1	-0.79	7.84×10−9	1.18	0.68
SLC6A4	Solute carrier family 6 member 4	-0.77	4.72×10−6	4.09	2.40

Abbreviation: FPKM, fragments per kilobase of transcript per million fragments mapped.