Table 2.
The nonlinear regression sigmoidal dose-response curve calculated the different IC50 values of ZnO-NPs for the breast cancer cell lines (MCF7 and MDA-MB-231) and HFF.
MCF7 | MDA-MB-231 | HFF | ||
---|---|---|---|---|
IC50 | 24 h | 11.16 μg/mL | 60.08 μg/mL | 26.3 μg/mL |
48 h | 7.736 μg/mL | 53.28 μg/mL | 24.76 μg/mL | |
72 h | 4.941 μg/mL | 55.83 μg/mL | 22.34 μg/mL | |
| ||||
Log IC50 | 24 h | 1.048 μg/mL | 1.779 μg/mL | 1.42 μg/mL |
48 h | 0.8885 μg/mL | 1.727 μg/mL | 1.394 μg/mL | |
72 h | 0.6938 μg/mL | 1.747 μg/mL | 1.349 μg/mL |
Abbreviations: MCF7: Michigan Cancer Foundation-7, HFF: human foreskin fibroblasts, IC50: the half-maximal inhibitory concentration, and log: logarithm.