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. 2020 Nov 20;2020:8817110. doi: 10.1155/2020/8817110

Table 2.

The nonlinear regression sigmoidal dose-response curve calculated the different IC50 values of ZnO-NPs for the breast cancer cell lines (MCF7 and MDA-MB-231) and HFF.

MCF7 MDA-MB-231 HFF
IC50 24 h 11.16 μg/mL 60.08 μg/mL 26.3 μg/mL
48 h 7.736 μg/mL 53.28 μg/mL 24.76 μg/mL
72 h 4.941 μg/mL 55.83 μg/mL 22.34 μg/mL

Log IC50 24 h 1.048 μg/mL 1.779 μg/mL 1.42 μg/mL
48 h 0.8885 μg/mL 1.727 μg/mL 1.394 μg/mL
72 h 0.6938 μg/mL 1.747 μg/mL 1.349 μg/mL

Abbreviations: MCF7: Michigan Cancer Foundation-7, HFF: human foreskin fibroblasts, IC50: the half-maximal inhibitory concentration, and log: logarithm.