Table 3.

The t-test was performed for the fold change values for caspase-3 and caspase-8 gene expression analysis in ZnO-NP-treated cells.

Variable		Caspase-3 expression (fold change) based on β-actin	p value	Caspase-3 expression (fold change) based on GAPDH	p value
HFF	Control	1.00 ± 0.13	0.020	1.00 ± 0.18	0.819
	Treatment	0.61 ± 0.11		0.952 ± 0.21
MCF7	Control	1.00 ± 0.22	0.239	1.00 ± 0.16	0.821
	Treatment	1.16 ± 0.23		0.959 ± 0.15
Variable		Caspase-8 expression (fold change) based on β-actin	p value	Caspase-8 expression (fold change) based on GAPDH	p value
HFF	Control	1.00 ± 0.12	0.020	1.00 ± 0.24	0.016
	Treatment	1.65 ± 0.20		2.56 ± 0.32
MCF7	Control	1.00 ± 0.14	0.1	1.00 ± 0.16	0.41
	Treatment	1.61 ± 0.15		1.33 ± 0.15

Abbreviations: MCF7: Michigan Cancer Foundation-7, HFF: human foreskin fibroblasts, miR: microRNA, and GAPDH: glyceraldehyde 3‐phosphate dehydrogenase.