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. 2020 Nov 23;13:4223–4234. doi: 10.2147/IDR.S278705

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© 2020 Cao et al.

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Bubble diagram of top 20 enriched GO terms and KEGG pathways for significantly differentially expressed genes (DEGs) between ATB and HD. (A) Top 20 ranked GO terms of up-regulated DEGs. (B) Top 20 ranked GO terms of down-regulated DEGs. (C) Top 20 pathways of up-regulated DEGs. (D) Top 20 pathways of down-regulated DEGs. Rich factor: the ratio of genes enriched in the GO term (KEGG) to the number of annotation genes, the enrichment degree was stronger with a bigger Rich factor. The size of dots indicates the number of genes in the GO term (KEGG).

Abbreviations: GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.