Fig. 3.

Memantine treatment has a partial effect on the motor performance of the Tg4-42^hom mice. a While Tg4-42^hom mice performed significantly worse compared with WT mice in the accelerating rotarod task, no improvement was detected upon chronic memantine treatment in Tg4-42^hom mice. b Memantine treatment showed a beneficial effect on motor performance in the balance beam task, with the memantine-treated Tg4-42^hom mice performing at WT levels. All data were given as mean ± SD. ***p < 0.001