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. 2020 Nov 27;11:6078. doi: 10.1038/s41467-020-19967-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Macrophage infiltration varied from minimal to severe in both rhesus and AGM infected with SARS-CoV-2. b Fluorescent immunohistochemistry in the lung of AGM and RM showing infiltration of CD16⁺ CD11b⁺ CD206⁻ macrophages (arrows), with lesser numbers of CD16⁺ CD206⁺ macrophages (arrowheads). Inset showing a higher magnification of CD16⁺ CD11b⁺ CD206⁻ macrophages (arrows). Asterix shows macrophages multifocally surrounding small airways in GH99. White: DAPI (nuclei); green: CD11b; red: CD16; blue: CD206.