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. 2020 Nov 27;11:6078. doi: 10.1038/s41467-020-19967-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Levels of IL-6 and IL-10 in plasma over time (pg/mL) (a) and b correlation between the ratio of IL-10 to IL-6 levels measured in plasma and the ranking of disease severity or c with pathology score (n = 8), by the Spearman correlation test. d Association between Kyn/Tryp ratio in plasma (pg/mL) and pathology score (n = 8, Spearman test). e Summary of immune events in the lungs and blood of SARS-CoV-2 infected animals, from the 1-acute phase 2-switch to Th2-type responses and 3-resolution phase.