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. 2020 Nov 25;4(11):nzaa165. doi: 10.1093/cdn/nzaa165

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© The Author(s) 2020. Published by Oxford University Press on behalf of the American Society for Nutrition.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Human plasma Trp and its major metabolites at baseline and after 1 y of PomJ or PL intake. (A) Trp, (B) KYN, (C) serotonin, (D) IPA, (E) IAA, and (F) IS concentrations. Data are presented as means ± SEMs (PomJ, n = 11; PL, n = 8). Within-group changes were analyzed by Wilcoxon signed ranks test (light capped line; PBL vs. PF; PJBL vs. PJF). Mann–Whitney test was used to see if the changes of Trp metabolites in the 2 groups are different (bold capped line; PL vs. PomJ). *Significantly different, P < 0.05. IAA, indole acetate; IPA, indole propionate; IS, indole sulfate; KYN, kynurenine; ns, nonsignficant; PBL, placebo baseline; PF, placebo final; PJBL, PomJ baseline; PJF, PomJ final; PL, placebo; PomJ, pomegranate juice.