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. 2020 Nov 27;10:20757. doi: 10.1038/s41598-020-77691-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Mean structural changes observed in the ruptured region of the injured tendon throughout the 12-week monitoring period. Thickness and echogenicity measured by B-mode US and vascularity assessed by Power Doppler. Values (N = 15/timepoint) are medians ± SD for the boxplot and means ± s.e.m. for the two line plots. Both echogenicity and vascularity are expressed in arbitrary units (a.u.). **p < .0001 vs baseline in injured leg (repeated measure ANOVA).