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. 2020 Nov 27;10:20785. doi: 10.1038/s41598-020-77624-8

Figure 5.

Figure 5

Experimental in vivo study design. In the vertical direction, the flow chart illustrates the VX2 rabbit tumor model and multimodal imaging on sequential time points. Left column: groups of three tumor-bearing rabbits were assigned to one MRI time point (day 14 + 15, 21 + 22, and 28 + 29 after tumor implantation) and euthanized following the scan. Right column: a group of three rabbits was assigned to two longitudinal MRI scans at each time point (14 + 15 and 28 + 29 days) and euthanized following the scan at time point 29.