Table 2.
List of the top 30 most upregulated genes in H. pylori G27 grown in biofilm condition (cutoff ratio ≥1 log2 fold-change and P-value < 0.05) using RNA-seq analysis. These genes are all expressed to higher levels in the biofilm cells.
| Name | Putative gene product | Fold-change |
|---|---|---|
| HPG27_166 | Hypothetical protein | 12.13 |
| HPG27_979 | VirC1 | 9.07 |
| HPG27_970 | VirB11-like | 6.43 |
| HPG27_1233 | m6A methyltransferase | 6.35 |
| HPG27_969 | Hypothetical protein | 5.93 |
| HPG27_1522 | Hypothetical protein | 4.72 |
| HPG27_270 | Chorismate mutase | 4.59 |
| HPG27_968 | Hypothetical protein | 4.46 |
| HPG27_509 | Glutamate racemase | 3.92 |
| HPG27_1066 | m5C methyltransferase | 3.89 |
| HPG27_324 | RluA, pseudouridine synthase D | 3.57 |
| HPG27_1059 | Hypothetical protein | 3.53 |
| HPG27_335 | Hypothetical protein | 3.39 |
| HPG27_269 | LysA, diaminopimelate decarboxylase | 3.29 |
| HPG27_671 | LptB, ABC transporter | 3.26 |
| HPG27_506 | CagB, cag island protein B | 3.18 |
| HPG27_271 | Hypothetical protein | 3.17 |
| HPG27_442 | m5C methyltransferase | 3.15 |
| HPG27_834 | Hypothetical protein | 3.13 |
| HPG27_669 | Hypothetical protein | 3.06 |
| HPG27_1331 | Hypothetical protein | 2.97 |
| HPG27_377 | TsaB, tRNA A37 threonylcarbamoyladenosine modification protein | 2.96 |
| HPG27_72 | PrfA, peptide chain release factor RF-1 | 2.96 |
| HPG27_1241 | Thiamine pyrophosphokinase | 2.73 |
| HPG27_652 | AcxB, acetone carboxylase subunit alpha | 2.69 |
| HPG27_589 | Hypothetical protein | 2.68 |
| HPG27_800 | Hypothetical protein | 2.63 |
| HPG27_571 | ABC transporter, permease | 2.62 |
| HPG27_47 | HypAV, type II restriction enzyme | 2.59 |
| HPG27_1299 | HpyAIV, type II restriction endonuclease | 2.59 |
| HPG27_660 | Hypothetical protein | 2.57 |