Fig. 4.

BrainAGE estimates and relationships with depressive symptoms. (A) Comparison of BrainAGE estimates (derived from reward ERPs) across groups (HC, healthy controls; SZ, schizophrenia subjects). (B) Relationship between depressive symptoms and BrainAGE gap scores in SZ; variables are residualized to account for the other predictors in Model 1 (Table 2). We removed one SZ subject with a BrainAGE estimate more than 3 SD above the mean from these analyses. Abbreviations: PANSS, Positive and Negative Syndrome Scale; resid, residuals.