Fig. 1.

(A) Fundus photograph of the right eye one week after the 3rd injection of brolucizumab. Near the disc there are areas of retinal whitening (white arrow). Plaques with associated sheathing are present in the superotemporal artery (yellow boxes). In addition, in the periphery there is boxcarring of the vessels (blue arrow). Multiple vitreous debris was also seen (green arrows). Optical coherence tomography insert demonstrates a large pigment epithelial detachment with subretinal fluid. (B) Fundus photography of the right eye 21 days after treatment with ranibizumab. Fundus has significant debris and haze (green arrow), worsening retinal whitening (white arrow), vascular sheathing nasal to disc (black arrow), and persistent boxcarring of the vessels. Optical coherence tomography insert reveals a collapsed pigment epithelial detachment with retinal atrophy and resolution of the subretinal fluid. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)