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. 2020 Nov 12;12(11):1088. doi: 10.3390/pharmaceutics12111088

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Tumor growth inhibition and prolonged life span in [²²⁵Ac]Ac-PP-F11N-treated mice. After tumor implantation, PBS or 30, 45, 60, 90, and 120 kBq of purified [²²⁵Ac]Ac-PP-F11N was administrated into A431/CCKBR tumor-bearing nude mice groups as indicated (n = 9, except for the control and 60 kBq group for which n = 18). The tumor growth (a) and the body weight curves (b) in different treatment groups. Values are shown as mean ± SD. (c) The survival rates presented as Kaplan-Meier curves of the control and [²²⁵Ac]Ac-PP-F11N-treated groups.