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. 2020 Nov 11;21(22):8467. doi: 10.3390/ijms21228467

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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FASN is not a direct c-MYC target in mouse and human HCC cell lines. (A) Effect of c-Myc silencing on the protein (upper panel) and mRNA levels of c-Myc (middle panel) and Fasn (lower panel) in the HCC3-4 mouse HCC cell line. (B) Effect of c-Myc silencing on the protein (upper panel) and mRNA levels of c-Myc (middle panel) and Fasn (lower panel) in the HCC4-4 mouse HCC cell line. (C) Effect of c-MYC silencing on the protein (upper panel) and mRNA levels of c-MYC (middle panel) and FASN (lower panel) in the SNU475 human HCC cell line. Tukey–Kramer test: at least p < 0.01; a, vs. control (untreated); b, vs. Scramble (solvent).