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Schematic representation of one of the pathways involved in Ins(1,4,5)P3-dependent Ca2+ release. GPCR, G protein-coupled receptor; IP3, Ins(1,4,5)P3; Ca++, calcium; ER, endoplasmic reticulum; IP3R, Ins(1,4,5)P3 receptor; DAG, diacylglycerol; PIP2, PtdIns(4,5)P2.
