Aβ	amyloid beta peptide
AD	Alzheimer disease
AOR	antioxidant response
APP	amyloid precursor protein
ARE	antioxidant response element
ATF6	activating transcription factor 6
ATP	adenosine triphosphate
BiP-GRP78	Binding immunoglobulin—Glucose regulated protein 78
CHOP (DDTI3)	DNA damage-inducible transcript 3
Chr21	chromosome 21
CN	central nervous system
DS	Down syndrome
Dyrk1A	dual specificity tyrosine phosphorylation regulated kinase 1A
eIF2α	eukaryotic initiation factor 2 alpha
ER	endoplasmic reticulum
GAPDH	glyceraldehyde 3 phosphate dehydrogenase
H1A	histone 1A
HSP	heat shock protein
IRE1	inositol-requiring enzyme 1
ISR	integrated stress response
NADPH	nicotinamide adenine dinucleotide phosphate
Nrf2	nuclear factor erythroid 2-related factor 2
OS	oxidative stress
PBMC	peripheral blood mononuclear cell
PERK	protein kinase R (PKR)-like endoplasmic reticulum kinase
PGK	phosphoglycerate kinase
PPP	pentose phosphate pathway
PKC	protein kinase C
PRDX	peroxiredoxin