Table 2.

The IC₅₀ (µM) of the synthesized compounds (6–14) against tested human cancer cell lines (MCF-7 and HCT-116).^a

Compound	MCF-7 b	HCT-116 c
6	79.80	89.20
7	30.70	34.30
8	73.30	107.50
9	34.40	36.70
10	25.90	32.70
11	98.20	102.30
12	5.80	14.80
13	1.26	17.30
14	40.60	46.80
Tam d	5.12	26.41
5-FU e	24.74	32.68

^a IC₅₀ values are the concentrations that cause 50% inhibition of cancer cell growth. Data represent the mean values ± standard deviation of three independent experiments, performed in triplicate; ^b breast cancer (MCF-7); ^c colorectal cancer (HCT-116); ^d Tam: tamoxifen; ^e 5-FU: 5-florouracil, which was used as a reference drug (positive control).