Table 1.
Litter size, implantation sites, and weaning rates of F0 dam, and nipple retention and survival rates of F1 offspring. *
| Treatment Group | Pregnant Mice (n) | Male Pups (n) | Litter Size | Nipple Retention (%) [PND 10] ** | Implantation Sites [PND 21] | Survival Rates (%) [PND 21] | Weaning Rates (%) [PND 21] |
|---|---|---|---|---|---|---|---|
| Control | 12 | 75 | 12.84 ± 0.44 | 4.90 ± 0.88 b | 13.12 ± 0.55 | 97.15 ± 1.31 a | 94.21 ± 2.36 |
| TDI | 12 | 73 | 13.07 ± 0.66 | 7.20 ± 1.50 b | 13.98 ± 1.83 | 94.16 ± 2.71 ab | 89.74 ± 1.81 |
| NOAEL | 13 | 77 | 12.88 ± 1.10 | 14.25 ± 1.60 a | 14.35 ± 1.33 | 92.75 ± 3.01 ab | 93.07 ± 1.93 |
| LOAEL | 14 | 82 | 12.92 ± 0.30 | 13.32 ± 1.88 a | 14.88 ± 0.38 | 89.67 ± 3.16 b | 93.43 ± 2.91 |
| EE control | 11 | 74 | 12.60 ± 0.33 | 12.94 ± 1.66 a | 13.35 ± 0.33 | 94.52 ± 1.78 ab | 92.45 ± 2.70 |
* Data were analyzed using one-way analysis of variance (ANOVA), where the differences letters (a, b, and ab) separated the statistical groups. ** Data generated from male pups only.