Figure 5.
Mechanisms of coronaviral infection of the brain. SARS-CoV-2 can enter the nervous system directly through the olfactory nerve, and also through blood circulation and neuronal pathways, resulting in neurological disorders. Ab: antibody; ACE2: angiotensin-converting enzyme 2; CSF: cerebrospinal fluid; ER: endoplasmic reticulum; TNF: tumor necrosis factor. [72].