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. 2020 Nov 12;10(11):852. doi: 10.3390/brainsci10110852

Figure 5.

Figure 5

Mechanisms of coronaviral infection of the brain. SARS-CoV-2 can enter the nervous system directly through the olfactory nerve, and also through blood circulation and neuronal pathways, resulting in neurological disorders. Ab: antibody; ACE2: angiotensin-converting enzyme 2; CSF: cerebrospinal fluid; ER: endoplasmic reticulum; TNF: tumor necrosis factor. [72].