OP	osteoporosis
IL-1	interleukin 1
TNF-α	tumor necrosis factor-alpha
RANKL	Receptor Activator of Nuclear factor Kappa-B Ligand
Ob-R	leptin receptor
MSCs	mesenchymal stem cells
SFRP1	secreted Frizzled-Related Protein 1
OA	osteoarthritis
IL-6	interleukin 6
Th17	T helper 17
IL-17	interleukin 17
ADRB2	beta-2 adrenergic receptor
RA	rheumatoid arthritis
Th1	T helper 1
Treg	T regulator
Dkk-1	dikkopf-1
TGF-ß	transforming growth factor-beta
PD	periodontitis
CD4	surface glycoprotein CD4
Th2	T helper 2
IL-8	interleukin 8
SLE	systemic lupus erythematosus
SSc	systemic sclerosis
PsA	psoriatic arthritis
BMI	body mass index
PMCA2	plasma Membrane Ca2+-ATPase
JAK	tyrosine-protein kinase JAK
STAT	signal transducer and activator of transcription
MAPK	mitogen-activated protein kinase
ERK	extracellular signal-regulated kinase
ER-α	estrogen receptor-alpha
NF-κB	Nuclear Factor-Kappa B
STAT3	Signal Transducer and Activator of Transcription 3
OPN	osteopontin
SPP1	secreted phosphoprotein 1
ER	estrogen receptor
PR	progesterone receptor
HER2	receptor tyrosine-protein kinase erbB-2
CRP	C-reactive protein
COX-2	cyclooxygenase 2
SAA1	serum amyloid 1
IL-10	interleukin 10
IDC	invasive ductal carcinoma
DCIS	ductal carcinoma in situ
RANTES	regulated upon activation, normal T-cell expressed and secreted
EMT	epithelial to mesenchymal transition
RUNX2	runt-related transcription factor 2
OBL	osteoblast-like cell
VDR	vitamin D3 receptor
BMP-2	bone morphogenetic protein 2
BMP-4	bone morphogenetic protein 4
PTX3	pentraxin-related protein PTX3
OCL	osteoclast-like giant cell
ICAM-1	intracellular adhesion molecule 1
PTHrP	parathyroid hormone-related protein
OPG	osteoprotegerin
ET-1	endothelin-1
HRT	hormone replacement therapies
SERM	selective estrogen receptor modulator
MORE	Multiple Outcomes Raloxifene Evaluation
CORE	Continuing Outcomes Relevant to Evista
NSABP	National Surgical Adjuvant Breast and Bowel Project
BCPT	Breast Cancer Prevention Trial
WT	wild type
PTHPTHrP	parathyroid hormoneparathyroid hormone related protein
FDA	Food and Drug Administration
US	United-States
SOST	sclerostin
LEC	lymphatic endothelial cells