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‘Eradicating-and-preventing’ approach to medical device-associated biofilms. After the biofilm has been eradicated (step 1), the surface of the implant should be further treated (step 2, for example by coating with antimicrobial agents or bioactive coating or with bioactive agents to enable rapid tissue-implant reintegration) to prevent infection recurrence. This proposed approach is essentially a combination of treating biofilms and preventing biofilm formation.
