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. 2020 Nov 16;21(22):8623. doi: 10.3390/ijms21228623

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Modulated lipids and small molecules in SARS-CoV-2 infection. Volcano plots of quantified lipids in positive (A) and negative (C) modes. A total of 265 lipids were modulated with a p-value < 0.05 and a fold change > 1.5. Hierarchical heat maps of quantified lipids in positive (B) and negative (D) modes, highlighting the two clusters of samples, with COVID-19 patients in red and healthy subjects in green. Panels (E,F) report the volcano plot of the quantified small molecules and the heat map, respectively.