Table 1.
Current available treatments for prostate cancer.
Treatment | Target | Risks and Recurrence |
---|---|---|
Prostatectomy | Efficient against localized and early- or advanced-stage tumors [13] | Moderate biochemical recurrence rate in localized tumors, risk of spreading beyond original location [22] |
Androgen deprivation therapy | Efficient against androgen- dependent carcinomas | Androgen insensitivity may develop leading to reoccurrence [23] |
Radiation therapy | Efficient against localized tumors or minimally metastasized tumors [15] | Low efficacy if tumor has developed beyond early stages, requiring combination treatments; higher mortality compared to prostatectomy [24,25] |
Chemotherapy | Primarily utilized to treat advanced-stage, metastatic, castration-resistant prostate cancer [26] |
Improves quality of life and slows disease progression in high-risk prostate cancer, but unlikely to cure it [27,28] |