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In vitro evidence of the effects of curcumin on prostate cancer stem cells.
| Cell Line | Curcumin Dosage | Effects | Reference |
|---|---|---|---|
| 22RV1 and DU-145 stem cells | 46.5 μM; 24 and 48h | ↓ Proliferation ↑ miR-145 ↓ lncRNA-ROR ↑ miR-3127 ↑ miR-3178 ↑ miR-1275 ↑ miR-3198 ↑ miR-1908 ↓ Ccnd1 ↓Cdk4 ↓Oct4 ↓CD44 ↓CD133 ↓CCND1 |
[101] |
| 22RV1 and DU-145 stem cells | 46.5 μM; 24 and 48 h to assess proliferation | ↓ Proliferation ↓ Cell migration ↑ miR-770-5p ↑ miR-411 ↑ miR-1247 ↓ miR-382 ↓ miR-654-3p |
[102] |
