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. 2020 Nov 11;25(22):5246. doi: 10.3390/molecules25225246

Scheme 1.

Scheme 1

(a) Previous work for the synthesis of dimer of 1,5-benzodiazepine-1,2,3-triazole; (b) synthesis of PHPs 11 and pyrrolo[3,4-b]pyridin-5-ones linked to 1,2,3-triazole; and (c) their complex analogs dimer 13 via the sequence: isocyanide-based multicomponent reactions (IMCR)/aza Diels–Alder-based domino process/double CuAAC click process.