ADC	Antibody drug conjugate
ATP	Adenosine triphosphate
BBB	Blood brain barrier
BiTE	Bispecific T-cell engager
CDK	Cyclin-dependent kinase
CNS	Central nervous system
CSF	Cerebrospinal fluid
CYP	Cytochrome P450
ecDNA	Extrachromosomal DNA
EGF	Epidermal growth factor
EGFR	Epidermal growth factor receptor
EIAED	Enzyme inducing antiepileptic drug
EORTC	European Organization for Research and Treatment of Cancer
ErbB	Erb-b2 receptor tyrosine kinase
FISH	Fluorescence in situ hybridization
GBM	Glioblastoma
Grb2	Growth factor receptor-bound protein 2
HB-EGF	Heparin-binding EGF-like growth factor
HER	Human epidermal growth factor receptor
IC50	Half maximal inhibitory concentration
IGFR1	Insulin growth factor receptor 1
IHC	Immunohistochemistry
INSIGhT	Individualized Screening Trial of Innovative Glioblastoma Therapy clinical trial
JAK	Janus kinase
KLH	Keyhole limpet hemocyanin
KRAS	Kirsten rat sarcoma
MAPK	Mitogen-activated protein kinase
MET	MET receptor tyrosine kinase; also known as hepatocyte growth factor receptor
MGMT	Enzyme O6-methylguanine-DNA methyltransferase
MMAF	Monomethyl auristatin F
MRI	Magnetic resonance imaging
NABTC	North American Brain Tumor Consortium
NCCTG	North Central Cancer Treatment Group
NSCLC	Non-small cell lung cancer
OS	Overall survival
PDB	Protein Database
PI3K	Phosphoinositide-3 kinase
PFS	Progression free survival
PKB	Protein kinase B; also known as Akt
PKC	Protein kinase C
PLCγ	Phospholipase C γ
RET	Rearranged during transfection
RT	Radiotherapy
RTOG	Radiation Therapy Oncology Group
SPECT	Single-photon emission computed tomography
STAT	Signal transducer and activator of transcription
TGF-α	Transforming growth factor-α
TKI	Tyrosine kinase inhibitor
TMZ	Temozolomide