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Effect of alpha-1 antitrypsin on ED-1 staining in tacrolimus-induced renal injury. (A) Immunohistochemical staining for ED-1 (200× magnification). (B) Quantitative analysis of ED-1 staining area. Data are presented as means ± standard errors; *** p < 0.001 vs. VH; ### p < 0.001 vs. TAC. Abbreviations: VH, vehicle group; AAT, alpha-1 antitrypsin treatment group; TAC, tacrolimus treatment group; TAC + AAT, tacrolimus and alpha-1 antitrypsin cotreatment group.
