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Continuous monitoring of 15 mm wound closure in each group over 21 days (A). The wound area (B) and wound closure (C) were calculated with NIH Image J analyzer by tracing the wound margin and calculating the pixel area. * p < 0.05 DM compared with the NDM group, § p < 0.05 DMR compared with the NDM group, # p < 0.05 DMR compared with the DM group.
