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ETC Complex I-IV enzyme activity in the (A) frontal cortex, (B) mesencephalon and (C) olfactory bulb of affected and control BD-IV rats at 27 dpn. All three regions from the mutant (affected) animals show a significant reduction in complex 1 (NADH dehydrogenase) and IV (cytochrome c oxidase) activities. The complex III and citrate synthase (CS) activities are increased.
