Table 1.
Characteristics of the study population.
| Anorexia Nervosa | Normal Weight | Obesity | p-Value | |
|---|---|---|---|---|
| N. subjects | 27 | 26 | 27 | - |
| Gender (male/female) | 1/26 | 7/19 | 3/24 | - |
| Age (years) | 26.9 ± 12.2 | 29.5 ± 8.1 | 36.7 ± 12.4 | <0.005 |
| Weight (kg) | 42.8 ± 8.7 | 64.8 ± 8.6 | 103 ± 16.25 | <0.005 |
| BMI (kg/m2) | 15.9 ± 2.2 | 22.1 ± 1.6 | 38.3 ± 4.8 | <0.005 |
| Plasma markers of adiposity | ||||
| SIRT1 (ng/mL) | 3.39 ± 2.2 | 2.47 ± 0.9 | 1.60 ± 1.8 | <0.005 |
| Adiponectin (µg/mL) | 6.39 ± 1.7 | 4.82 ± 1.3 | 4.3 ± 1.7 | <0.005 |
| Leptin (ng/mL) | 5.63 ± 7.6 | 6.13 ± 6.0 | 23.75 ± 17.7 | <0.005 |
| Districts of adiposity | ||||
| Total FM (%) | 17.41 ± 6.9 | 27.04 ± 6.2 | 41.04 ± 4.1 | <0.005 |
| Trunk FM (%) | 12.3 ± 6.1 | 22.7 ± 6.7 | 39.1 ± 4.2 | <0.005 |
| Abdominal VAT (g) | 83.2 ± 62.6 | 223.8 ± 102.6 | 575.6 ± 226 | <0.005 |
| EFT (mm) | 4.0 ± 0.7 | 6.5 ± 0.7 | 8.2 ± 0.7 | <0.005 |
| Liver Steatosis (degrees) * | ||||
| Absent | 3 (11%) | 21 (81%) | 0 (0%) | <0.005 |
| Mild | 24 (89%) | 5 (19%) | 19 (70%) | <0.005 |
| Moderate/severe | 0 (0%) | 0 (0%) | 8 (30%) | <0.005 |
SIRT1, sirtuin 1; BMI, body mass index; FM, fat mass; VAT, visceral adipose tissue; EFT, epicardial fat thickness. * The severity of liver adiposity was based according to the brightness of the liver estimated as a numerical value: 0 = absent; 1 = mild lipid accumulation; 2 = moderate/severe lipid accumulation. Values are expressed as means ± SD.