Figure 2.

PBMCs expression pattern of the specific splicing machinery components after three years of follow-up under two healthy dietary patterns (low-fat (LF) diet and Mediterranean (Med) diet). mRNA expression levels (adjusted by a normalization factor (NF) calculated from the expression level of GAPDH and ACTB) of specific spliceosome components and splicing factors in the PBMCs from all the participants included in the study. Values represent the mean ± SEM. Asterisks indicate values that significantly differ from non-T2DM subjects (t-test: *, p < 0.05; ***, p < 0.001).