Table 3.
Summary of called variants.
| Total Variants | SureS V6 | TS DNA Na | TS DNA Ex | Nxt DNA Ex (125 bp) | Nxt DNA Ex (350 bp) | Nxt DNA Ex (450 bp) | Ill DNA Enr |
|---|---|---|---|---|---|---|---|
| Strict target | 54,418 ± 681 | 68,401 ± 1118 ** | 65,247 ± 4410 ** | 66,592 ± 1603 ** | 75,309 ± 917 ** | 76,809 ± 3206 ** | 83,362 ± 4984 ** |
| Padding | 111,588 ±1326 | 98,100 ± 602 ** | 68,750 ± 5408 ** | 72,422 ± 2016 ** | 110,479 ± 1172 ns | 112,823 ± 2568 ns | 99,494 ± 10,120 ** |
SureS V6: SureSelectQXT Human All Exon V6, TS DNA Na: TruSeq DNA Nano, TS DNA Ex: TruSeq DNA Exome, Nxt DNA Ex: Nextera DNA Exome, Ill DNA Enr: Illumina DNA Prep with Enrichment. bp: base pair. Numbers refer to average ± standard deviation. Statistical significance of the differences between enrichment protocols compared to SureSelectQXT V6 indicated as: ns p > 0.05; * p ≤ 0.05; and ** p ≤ 0.01.