Table 2.
Bacterial biofilm-targeted MSNs as antimicrobial delivery systems.
| Targeting Ligand 1 | Drug Loaded | Nanocarrier 2 | Bacterial Biofilm 3 |
Assay | Ref. |
|---|---|---|---|---|---|
| DAMO | Levofloxacin | MCM-41 DAMO-MSNs | S. aureus | In vitro | [47,68] |
| G3 | Levofloxacin | MCM-41 G3-MSNs | E. coli | In vitro | [47] |
| ConA | Levofloxacin | MCM-41 ConA-MSNs | E. coli | In vitro | [69] |
1 DAMO: N-(2-aminoethyl)-3-aminopropyltrimethoxy-silane; G3: poly(propyleneimine) third-generation dendrimer; ConA: concanavalin A. 2 MCM-41 DAMO-MSNs: MCM-41 type MSNs functionalized with DAMO; MSNs-ConA: MCM-41 type MSNs decorated with ConA. 3 E. coli: Escherichia coli; S. aureus: Staphylococcus aureus.