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. 2020 Nov 16;9(11):401. doi: 10.3390/biology9110401

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(a) Cumulative tally of unique membrane protein structures deposited in the Protein Data Bank (PDB) adapted from the Membrane Proteins of Known 3D Structure database [4]. (b) Membrane Protein Laboratory (MPL) projects classified by target origin in 2008/9 (29 projects) and 2018/19 (46 projects). (c) Number of membrane protein structures solved each year by electron diffraction (ED), electron microscopy (EM), X-ray crystallography and nuclear magnetic resonance spectroscopy (NMR) (d) accepted MPL projects by requested technology platform in 2008/9 (29 projects) and 2018/19 (46 projects). Cloning and expression were not supported in 2008/9.