Figure 2.

Multiple Sequence alignment of SOX1 protein. (A) Multiple Sequence alignment (MSA) for SOX1 protein focusing on the highly conserved motif ₃₁₈VKSEPSGSP₃₂₆ (underlined in red). (B) MSA between members of the SOXB1 subgroup, focusing on the consensus motif named as ‘SOXB1 consensus motif’ used to further search protein databases. Figure generated using the EMBL-EBI resources, ClustalOmega alignment output page [17]. (C) Predicted PTMs within SOXB1 consensus motif. Conserved amino acids are shown in capital letters. P; Phosphorylation, sm; Sumoylation. IBS illustrator was used to produce the diagram [22].