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. 2020 Nov 16;12(11):3524. doi: 10.3390/nu12113524

Figure 3.

Figure 3

Effect of monobutyrin supplementation on intestinal permeability in mice fed either an LF or HF diet for 6 weeks. (A) fluorescein isothiocyanate-dextran (FD)4 flux (paracellular pathway) and (B) horseradish peroxidase (HRP) flux (transcellular pathway) in the colon of mice fed either a LF or HF with or without 0.25% MB supplementation for 6 weeks. Two-way analysis of variance followed by Sidak’s post hoc test was used to determine differences among groups. Values are means ± SEMs; n = 2–3/group. Significant (p < 0.1) main effects are listed on graphs where they occur. FD4, fluorescein isothiocyanate-dextran 4000; HRP, horseradish peroxidase; HF, high-fat diet; LF, low-fat diet; Con, drinking water only control; MB, monobutyrin as 0.25% MB (w/v) in drinking water.