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Activities of enzymes known to be induced by Nrf2 in NAC-treated mice. Four-week-old male mice (C57BL/6Jrj) chronically received NAC for 20 weeks via the drinking water (1 g NAC/100 mL). NQO1, TXNRD, and SOD activities were measured photometrically in (a,d,g) duodenum, (b,e,h) liver, and (c,f,i) spleen. The data are shown as mean ±SD and were calculated by unpaired t-test. # p < 0.05, ## p < 0.01, ### p < 0.001 vs. −NAC (NAC effect).
