Table 1.

Effects of chronic NAC treatment on the body and spleen weight, the hepatic GSH content, and hepatic GPX activity in vivo. Four-week-old male mice (C57BL/6Jrj) chronically received NAC for 20 weeks via the drinking water (1 g NAC/100 mL). The data are shown as mean ±SD (n = 10) and were calculated by unpaired t-test. ^# p < 0.05 vs. −NAC (NAC effect).

	−NAC	+NAC
body weight [g]	31.2 ± 2.5	30.7 ± 2.9
spleen weight/body weight [mg/g]	2.6 ± 0.4	3.1 ± 0.4 #
total hepatic GSH content [µM]	65.4 ± 8.3	70.2 ± 6.9
hepatic GPX activity [mU/mg liver]	894.0 ± 84.1	952.9 ± 103.3