Table 2.
Overview of expression data of EGFR, Her3, Her3, Her4 and c-Met in oropharyngeal squamous cell carcinoma.
| Receptor (N) | Tissue | Level | N (%) | Receptor (N) | Tissue | Level | N (%) |
|---|---|---|---|---|---|---|---|
| membranous EGFR (70) | normal oral tissue | Mean | 112 | membranous Her4 (67) | normal oral tissue | Mean | 127 |
| tumor tissue | Median | 107 | tumor tissue | Median | 98 | ||
| Range | 5–206 | Range | 9–276 | ||||
| Expression > 10 | 66 (94) | Expression > 10 | 65 (97) | ||||
| Overexpression | 32 (46) | Overexpression | 18 (27) | ||||
| Low | 37 (53) | Low | 39 (58) | ||||
| High | 33 (47) | High | 28 (42) | ||||
| membranous Her2 (68) | normal oral tissue | Mean | 41 | nuclear Her4 (78) | normal oral tissue | Mean | weak |
| tumor tissue | Median | 0 | tumor tissue | Median | none | ||
| Range | 0–117 | Range | none-strong | ||||
| Expression > 10 | 10 (15) | Expression | 34 (45) | ||||
| Overexpression | 3 (4) | Overexpression | 8 (10) | ||||
| Low | 44 (65) | Low | 12 (15) | ||||
| High | 24 (35) | High | 5 (6) | ||||
| membranous Her3 (66) | normal oral tissue | Mean | 114 | membranous c-Met (65) | normal oral tissue | Mean | 37 |
| tumor tissue | Median | 71,5 | tumor tissue | Median | 7 | ||
| Range | 0–152 | Range | 0–220 | ||||
| Expression > 10 | 57 (86) | Expression > 10 | 30 (46) | ||||
| Overexpression | 11 (17) | Overexpression | 15 (23) | ||||
| Low | 35 (53) | Low | 43 (66) | ||||
| High | 31 (47) | High | 22 (34) |