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. 2020 Nov 13;9(11):3653. doi: 10.3390/jcm9113653

Figure 1.

Figure 1

Illustration of CD40/CD40L regulated intracellular signaling. CD40 receptor activates different types of TRAFs upon stimulation and triggers signaling cascades including the PI3K, NF-κB, and p38/ERK pathways. (Figure created with BioRender.com).